Chromosome Screening

Chromosome Screening

The purpose of chromosome screening is to analyze to be selected in transferring normal embryo for higher successful of pregnancy and also to avoid miscarriage. It is known that aneuploidy – any embryo with too many or too few chromosomes which most likely that reason for failure in the treatment.

Preimplantation Genetic Screening (PGS), also known as aneuploidy screening, usingPGD 5 Probes and Next Generation Sequencing (NGS) is widely used to select competent embryos, free of chromosome abnormalities, for embryo transfer. This embryo selection improves clinical outcomes by achieving a higher implantation rate and a reduction in miscarriage rates.

We provide 2methods of chromosome screening.

  1. PGD 5 Probes – this method is to screened for the abnormality in chromosome number 13, 15, 21 and X-Y (Sex chromosome), by using FISH (Fluorescent in situ hybridization) requires removal a single cell on Day 3 or several cells on day 5 or 6 of embryo development. The FISH test is done using fluorescent probes that bind to certain specific chromosomes.
  2. NGS – this method is to screen for the abnormality in all humanchromosome, including X-Y chromosome (Sex chromosome). Next-Generation Sequencing (NGS) is the latest technology in genetic testing all 23 pair’sof human chromosomes and sex chromosome at a more comprehensive level and with high resolution. NGS provides the ability to screen embryos from chromosomes errors such as Down syndrome and other similar aneuploidy conditions.